Western Cape police have launched a manhunt for gunmen following a shooting incident on Wednesday evening in Manenberg that left one person dead and several injured, including a police official.

A 22-year-old man was shot and killed, and four men, aged 24, 35, 36 and 48, as well as a woman, aged 56, were injured.

Police who were already deployed in the area responded to gunshots but also came under fire. One officer sustained injuries. The injured victims were transported to nearby hospitals for medical treatment.

The chaos ensued after a silver grey car drove down Rio Grande Walk, abruptly stopped and started firing random shots at people standing in front of the premises.

Police officers patrolling the area responded to the sound of the gunshots, and upon their arrival on the scene, the suspects fired several shots at them.

A 42-year-old SAPS officer was injured by shrapnel to his head. The suspects fled the scene and have yet to be arrested.

Manenberg police registered a murder and six counts of attempted murder for investigation. The incident is believed to be gang-related.

Operational forces have been deployed in the area to stabilise the situation and to ensure increased police visibility within the affected community.